Abiodun Falodun and Osahon Obasuyi
Keywords: K. senegalensis, stem bark extract, MRSA, bacterial infections
Abstract: Khaya senegalensis is an herbal medicinal plant, used locally in Nigeria and South Africa for the treatment of cough and sexually transmitted diseases. This antibacterial activity prompted the phytochemical and antibacterial investigation of this herbal plant. The stem bark of K. senegalensis was subjected to phytochemical studies using standard experimental procedures testing for secondary metabolites. The crude extract was evaluated for its antimicrobial activity using methicillin resistant strains of Staphyloccocus aureus MRSA. The result of the study revealed the presence of alkaloids, saponins, tannins and flavonoids in the plant extract. The extract exhibited significant antibacterial and MRSA activities against the tested organisms. The study therefore provides natural source for drugs used for the treatment of methicillin resistant strains (MRSA) infections.
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