M Zaheer Khan, Ghazala Yasmeen, Shahnaz Parveen, Adil Akbar, Afsheen Zehra and Babar Hussain
Keywords: Euphlyctis cyanophlyctis, effects, permakil, sandaphos, liver, kidney
Abstract: The present study was done to investigate the effects of pyrethroid and organophosphate on liver and kidney cells of adult Euphlyctis cyanophlyctis. During the study, the frogs were treated with two concentrations of both the pesticides. Under the effect of Permakil (pyrethroid) the liver cells of treated frog showed necrosis. The cells were clustered and they were collectively formed. The hepatic parenchyma with focal disruption of lobular architecture and focal necrosis was observed. No further significant calcification was observed. Under the effect of Permakil the histological section of kidney of treated frog showed foci of necrosis. Renal parenchyma with necrosis and tubular atrophy was observed. No significant change in the glomerulus was identified. In the case of Sandaphos (organophosphate) the multinucleated, melanomacrophages were observed in histological section of liver of treated frogs. Malignant neoplasmic cells were also found. Hepatic tissue showed focal disruption of lobular architecture. Focal necrosis was identified. Under the effect of Sandaphos hypertrophy and the ruptured cells were identified in the kidney sections of treated frogs. Atrophy, necrosis and inflammation were observed in nephrons.
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