M Gulfraz, N Fatima, Z Parveen and S Mahmood
Keywords: Antimicrobial activity, medicinal plants, drugs, health.
Abstract: Plants are biosynthetic laboratories for many useful compounds those are playing important role in human health. Ingredients of some medicinal plants are very much effective against bacterial growth and can be used to minimize their activities. A study was conducted to assess the possible affects of berberis lyceum Royle against the 18 bacteria, 4 fungi and yeast strains. The root extracts were prepared in methanol and aqueous media. Where as antimicrobial activities were assessed by using Disc diffusion method and Micro dilution assays. It was observed that methanol and aqueous root extracts of berberis lyceum were highly effective against different bacteria and fungi. The methanol extracts (135-260 ?g/l) have inhibited growth of microorganisms more effectively as compared to aqueous extract (120-230 ?g/l). The results obtained in present study indicates that root of berberis lyceum contained some phyto chemicals with antimicrobial activity and could be useful for pharmaceutical industries for development of new drugs for human and animal health.
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